Over the past decade, a continued discussion point has been the idea around analyzing samples on Ligand Binding Assay (LBA) platforms in singlet (one well) versus the standard duplicate analysis (Single sample added to two different wells). In the recent M10 Bioanalytical Method Validation Guideline issued for guidance in June…

At KCAS Bio, we continuously seek ways to improve our processes with sound, logical, scientific, and business-related methods.  One of these areas of evaluation has been sample preparation.  We have improved various segments of bioanalysis (drying for unstable analytes, liquid handling, and plate-based assays for increased efficiency).  We can also…

Pioneers of RNA Medicine: The Collaborative Journey of Katalin Karikó and Drew Weissman The entire world benefited from their research in 2020. Despite facing skepticism, their collaborative efforts led to groundbreaking discoveries in RNA biology and immunology. They jointly received the Nobel Prize in Physiology or Medicine in 2023.

KCAS Bio SAS (Active Biomarkers SAS) based in Lyon France, a full-service bioanalytical and biomarkers solutions provider is very pleased and proud to share that it successfully opened a new Good Laboratory Practice (GLP) Test Facility to provide GLP-grade bioanalytical methods in the context of preclinical studies. Since November 2023,…

As an emerging and growing application, spectral flow offers capabilities beyond what is possible with conventional flow. Its unique capabilities make it a powerful tool for researchers aiming to extract more information from each sample and push the boundaries of discovery. Join us in this post as we explore…

In the scientific field, the often neglected fifth sense, the sense of smell, contributes to broadening our understanding of various phenomena, particularly in the field of biomarkers.Here, we will guide you along our lines of thought on the importance of our olfactory sense, and how it contributes to scientific exploration…

Clients typically will come to us saying that they have a therapy, and it is going to address these targets, this disease, to treat certain patients. They want to know how we can best understand what’s happening and how the immune system will respond. We need to know what cells…

One of the coolest things we’re doing here at KCAS Bio is definitely validating new instruments and new software. We start off with the Cytek systems of course, and then we’re adding in FCS Express, we’re applying both of those tools ’cause that’s really all they are at the…

KCAS has recently moved from a space that was extremely tight – even for the operations we had at the time – to an enormous new modern lab building that is purpose-built for the type of work that allows all of our workflows to be more efficient, more scalable,…

For the last decade or so, the outsourcing of crucial research functions by pharmaceutical and biotechnology companies has become increasingly common and has resulted in the rapid growth of the Contract Research Organization (CRO) industry. But the selection of the best CRO partner to work on your critical research programs…

Rosalind Franklin: Unveiling the DNA Helix and Beyond She is known for the celebrated photo 51 She is famous for her X-rays An American university and an English research institute bear her name  Her name is Rosalind Franklin. Her crucially important X-ray crystallography work was key to…

Flow Cytometry has been an invaluable tool for scientific advancement in immunology, oncology, stem cell research, infectious disease, vaccines, and drug development research. As a versatile and powerful technique, it can be used in various ways and tailored to meet your research needs.  Applications include precise evaluation of cell…