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Flow Cytometry Blog

Flow Cytometry for Cell Cycle Analysis

Posted on: August 14, 2019

The cell cycle is a defining characteristic of living organisms. In multicellular organisms, including humans, the cell cycle governs the duplication of cells in a manner that assures accurate DNA replication and cell division. Cell cycle regulation is considered such an essential element of biology that Leland H. Hartwell, R. Timothy Hunt and Paul M. Nurse were recognized with the 2001 Nobel Prize in Physiology for their discoveries of "key regulators of the cell cycle."

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Three Reasons to Partner with a Specialty CRO

Posted on: August 07, 2019

When it comes to handing over your precious research samples to a contract research organization (CRO), how do you know you are outsourcing to the right company? Larger CROs seem to offer every type of analysis available, from genomics to histopathology. But specialty CROs may be a better option, especially if you need sophisticated techniques and data analysis.

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Why Outsource Flow Cytometry?

Posted on: July 31, 2019

Make Your Decision With These 5 Questions

You have just gotten approval to start a big phase 1 clinical trial and 172 precious blood samples are about to come through your door in about two months. What do you do? Do you clone yourself and your outstanding flow cytometry skills? Do you consider skipping sleep for a few weeks? Do you panic? Perhaps, you should consider outsourcing your flow cytometry analysis ...

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Where did my cells go? On summer vacation???

Posted on: July 24, 2019

Have you ever started a flow cytometry run and you cannot see any cells? This can be an alarming feeling, but some straightforward troubleshooting can usually help you find your missing cells. Check out these three questions to tackle common issues associated with disappearing cells.

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Whole Blood Flow Cytometry Assays for Immuno-Oncology

Posted on: July 03, 2019

Flow cytometry is becoming a standard tool in clinical and translational immuno-oncology (IO) research because it allows researchers to monitor dynamic changes in the immune system and can be customized to study different cancers. Flow cytometry-based immunophenotyping assays using whole blood are especially well suited to IO research because various cells subsets can be profiled in a single assay including naive CD4+ and CD8+ T cells, central and effector memory T cells, regulatory T cells, B cell subsets, NK cells, monocytes/macrophages, and dendritic cell subsets. These assays can be used for evaluating all types of IO therapies including checkpoint inhibitors, adoptive cell therapies, and cancer vaccines.[1]

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Computational Cytometry | Flow Cytometry Data Analysis in the Era of Quantitative Data Science
 

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