During the initial outbreak of the SARS-CoV-2 Global pandemic, children, in general, appeared to be relatively resilient against the virus, with only 2% of reported cases in patients under 20 years old; and world-wide, epidemiologists identified older populations with underlying conditions as being at most risk (Ludvigsson, J. F. 2020).
Flow Cytometry Blog
Advances in immunology data analysis have taken this field into the realm of “Big Data.” Flow cytometers can now measure dozens of parameters, and complementary techniques like mass cytometry can deliver data that requires sophisticated data analysis methods. Modern data analysis approaches have also revolutionized personalized immunotherapy and improved diagnostics.
Immunotherapeutic molecules currently being used in the clinic are powerful immune modulators, but their effectiveness can be inconsistent between patients. Clinicians and scientists use different assays to evaluate why immunotherapies fail in the clinic. The flow cytometry-based receptor occupancy (RO) assay is a critical tool for evaluating the effectiveness of immunotherapies in the clinic. Here are three features of flow cytometry-based RO assays that give them clinical value.
High quality flow cytometry results start with proper collection, processing and storage of cell specimens. Several factors determine which type of test tube to use for sample collection, including the cell type you are studying, and your preservation and shipping needs.