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Flow Cytometry Blog

Using Cell Sorting to Characterize Cell Lines

Posted on: May 16, 2019

Cell sorting is not limited to studying cells derived from blood or tissue samples, but it is also a valuable too for characterizing cell lines. Cell lines are critical to basic research studies as well as biopharmaceutical product development and production. Consider these cell sorting applications for your cell line needs.

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Panel Preferences: Which Markers are Best for Staining Regulatory T Cells?

Posted on: May 01, 2019

Regulatory T cells (Tregs) are an important cell subpopulation because they can modulate immune responses that target self-antigens but are also associated with poor outcomes in cancer patients. Tregs are found in peripheral blood and are defined by both surface and intracellular markers, but there is still some debate as to the optimal staining panel for monitoring Tregs, particularly during immunotherapeutic interventions for cancer therapy and autoimmune diseases. 

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Fixed or Fresh: What’s better for preclinical flow cytometry evaluations?

Posted on: April 18, 2019

Flow cytometry analysis is a critical technique for guiding preclinical drug development. Flow cytometry data can provide mechanistic insights and define potential biomarkers that correspond to clinical outcomes. But getting the most out of your preclinical flow cytometry analysis may hinge on how your cell samples are handled, specifically whether you are working with fresh cells or fixed cells.

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Computational Cytometry | Flow Cytometry Data Analysis in the Era of Quantitative Data Science
 

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