Toxicology screening is essential to any preclinical study, and flow cytometry-based toxicology assays are a fast and practical approach. Different animal models are used for toxicology studies, including rodents, dogs and non-human primates. One commonly used technique is the micronucleated erythrocyte endpoint assay, which measures DNA damage induced by exposure to experimental drugs or biologics. This method has been adapted into a validated flow cytometry-based assay and can use erythrocytes from different species. Consider these factors when selecting the best toxicology screening method.Read the full article »
You have just gotten approval to start a big phase 1 clinical trial and 172 precious blood samples are about to come through your door in about two months. What do you do? Do you clone yourself and your outstanding flow cytometry skills? Do you consider skipping sleep for a few weeks? Do you panic? Perhaps, you should consider outsourcing your flow cytometry analysis ...
Walk through the who, what, where, when, and why of outsourcing flow cytometry and make the best decision for your next flow cytometry-based project.Read the full article »
High quality flow cytometry results start with proper collection, processing and storage of cell specimens. Several factors determine which type of test tube to use for sample collection, including the cell type you are studying, and your preservation and shipping needs.Read the full article »