Cell sorting is not limited to studying cells derived from blood or tissue samples, but it is also a valuable too for characterizing cell lines. Cell lines are critical to basic research studies as well as biopharmaceutical product development and production. Consider these cell sorting applications for your cell line needs.Read the full article »
Immune cell infiltration is essential for anti-tumor responses because immune cells must be able to be in close proximity to tumor cells for these responses to be effective. Flow cytometry is a flexible and powerful tool for detecting and monitoring the presence of infiltrating immune cells, or TIL, and can be customized to detect any immune cell subset.
Consider these questions as you think about assessing infiltrating immune cells with flow cytometry in your Immuno-Oncology (IO) research.Read the full article »
Regulatory T cells (Tregs) are an important cell subpopulation because they can modulate immune responses that target self-antigens but are also associated with poor outcomes in cancer patients. Tregs are found in peripheral blood and are defined by both surface and intracellular markers, but there is still some debate as to the optimal staining panel for monitoring Tregs, particularly during immunotherapeutic interventions for cancer therapy and autoimmune diseases.Read the full article »