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News from FlowMetric

  • To Fix or Not to Fix – How to Handle Clinical Samples for Flow Cytometry View Post Summary

    Most flow cytometry samples are processed, stained and then run on a flow cytometer, and these protocols may take a few hours but can also span the greater part of a day. Protocols take even longer when many samples needed to be handled, which is often the case with clinical samples. How do you handle staining and running large numbers of clinical samples while also trying to pull an all-nighter? In some cases, a fixative can be added to stained cells so they can be preserved in their stained state, refrigerated, and run on a flow cytometer at a later time. Consider these factors to help you determine if cell fixation is a good option.

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  • Flow Cytometry Beyond Basic Research: Best Practices In GLP For Flow Cytometry Assays View Post Summary

    Flow cytometry assays are important for preclinical and clinical research, however, it is vital to understand the level of compliance required for the stage of research you are completing.  Flow Cytometry assays completed for toxicology and safety assessments are required to be in compliance of Good Laboratory Practices (GLP), on the other hand, basic research or discovery/exploratory studies can be non-GLP.  GLP refers to a set of standards for laboratory studies to be planned, performed, monitored, reported, and archived. Preclinical and clinical studies must be GLP-compliant in order to be submitted for review by regulatory agencies like the FDA. Consider these three points if you find yourself in need of a GLP-compliant flow cytometry assay. 

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  • Fast and Furious Flow Cytometry: HTS Assays View Post Summary

    Flow cytometry is becoming an increasingly popular tool for high-throughput screening (HTS) assays for identifying potential new drugs or biologics. Most users are acquainted with flow cytometers that use individual tubes for sample collection, but flow cytometers can be equipped with HTS attachments for automated sample collection for multi-well plates. Check out these benefits of using flow cytometry for HTS assays.

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