FlowMetric specializes in delivering state-of-the-art cell sorting and flow cytometry services. We support programs across the entire drug development value chain for our pharmaceutical, biotech and CRO partners with speed and expertise. Learn More About Us

Why Choose FlowMetric

FlowMetric was established to deliver decision-enabling data on programs that matter the most to you. Partners choose us because of our expertize, our focus, our approach and results we have delivered.

Learn More

FlowMetric Fast Facts

  • Over 100 clients ranging from large pharma, biotech, to the hospital setting
  • Ability to measure up to 16 parameters simultaneously
  • Expertise in multiple species & sample types
  • Multi-City site experience, domestic & international
  • Philadelphia Business Journal award for "Best CRO" in 2012

News from FlowMetric

  • Venturing Into Validation View Post Summary

    Best Practices in Assay Validation

    Flow cytometry is a well-established approach used in numerous clinical assays across the globe. But like most assays used in a clinical setting, flow cytometry assays typically need to be validated before they can be used for diagnostic or clinical research purposes.

    Assay validation is done to demonstrate that a method is accurate, specific, reproducible and robust over a designated range of measurement. Flow cytometry is considered an analytical method, and according to the FDA, flow cytometry assays need to meet specific analytical method validation criteria. A validated assay can then be used in situations requiring GLP/GCP (good laboratory/clinical practice) compliance, like a clinical trial or routine diagnostic test.

    Chelsea Riveley, an associate director at FlowMetric, Inc. explains the nuts and bolts of flow cytometry assay validation. “Validation is usually what follows assay development,” Riveley said. Validation is done to confirm that the method is fit for its intended use and the assay meets specific criteria with respect to stability requirements, accuracy, precision, specificity, detection limit, limit of quantitation, linearity and range, ruggedness, and robustness.

    Read the full article »
  • Keep Calm and Contract your Cytometry View Post Summary

    Top 5 Things to Look for in a Flow Cytometry CRO

    There comes a moment when the flow cytometry work can be too much. Sometimes it’s the big “make-or-break” experiment that has to go just right, or sometimes it’s the monthly batches of clinical trial samples that have to be handled, on a Saturday, with swift, deft hands, and you’re the only one qualified for the job. That’s when you either break down in tears of exhaustion and frustration, or you consider finding some help. Now most investigators aren’t in a position to hire and train new staff for cytometry work, but there is high quality and reliable alternative—A contract research organization (CRO).

    Read the full article »
  • Top 3 Things To Consider When Developing A Clinical Flow Cytometry Assay View Post Summary

    Flow cytometry has been developed and used as a clinical tool since the invention of the first cytometers in the 1970s. At present, flow cytometry is considered essential for many routine clinical diagnostics, including assays for leukemia and lymphoma, stem cell enumeration, solid organ transplantation, HIV infection status, immunodeficiencies, and hematologic abnormalities. Many scientists involved in clinical trials or drug development are faced with developing clinical flow cytometry assays for multiple phases of clinical development.

    If you find yourself starting to plan a clinical flow cytometry assay, here are the top 3 issues to think about as you plan your experiment.

    Read the full article »